6 Common Questions Around a Positive BCL6 Result

Planning for parenthood can be difficult if a patient has trouble with failed IVF or miscarries a pregnancy. Fertility experts recommend that a patient undergo a BCL6 test to help them identify the cause of infertility. In case of positive results, it may prove that the patient is suffering from positive BCL6 & endometriosis. Following a BCL6 result that is positive, these are some common questions:

1.) What Are the Chances of Getting Pregnant?

Fertility specialists use the BCL6 test to identify BCL6 associated with endometriosis. This test helps clinicians diagnose underlying causes of infertility and predict IVF outcomes. A positive BCL6 test result indicates potential inflammation of the uterine lining, which could affect your ability to get pregnant.

A woman can get pregnant with a positive BCL6 result and endometriosis using IVF. The chances of getting pregnant are low, about 12% on the next transfer. When a patient undergoes treatment, the chances of getting pregnant often increase.

2.) What Are the Treatment Options for BCL6 & Endometriosis?

Health professionals recommend some potential treatments if the results of the tests are positive. The success rate of the subsequent IVF may rise with the aid of these procedures. Available treatment options include the following:


This is a surgical process that involves inserting a fiber optic instrument through the abdominal wall. The device views organs inside the abdomen and removes visible endometriosis, minimizing inflammation.

A laparoscopy can be expensive and only carried out by a skilled surgeon. This has made it fall out of favor for the last two decades. A BCL6 test is becoming preferred to laparoscopy. It is cost-effective in helping to identify whether endometriosis is the cause of the symptoms.

Hormonal Suppression Therapy

BCL6 (B cell lymphoma-6) is a protein secreted during women’s menstrual cycle with endometriosis. It is responsible for uterine inflammation. To ascertain whether a woman has an inflammatory condition caused by endometriosis, a test is done on an endometrial sample.

IVF Patients may receive 60 days of hormonal suppression therapy, through a two-dosage injection such as Depot Lupron. The hormones may stop the menstrual cycle. They also suppress inflammation long enough for the embryo to attach and grow on the uterine lining.

3.) What Is the Link Between a Positive BCL6 Test & Endometriosis?

If the test is positive, it signifies that BCL6 has been detected, indicating inflammation of the uterine lining, or endometriosis. Endometriosis surprises many women who have never had any symptoms other than their recent fertility issues. Most women who take the BCL6 test and get positive results appear symptom-free. This is called “silent endometriosis” and is likely the cause of their unexplained infertility.

4.) What Are the Chances of a Successful Pregnancy After Tests Show Positive BCL6 and Endometriosis?

Endometriosis in women makes it hard for them to conceive naturally or through other treatments. In some cases, when conception occurs, it may affect pregnancy, leading to an increased risk of miscarriages. IVF Patients with silent endometriosis can benefit from a BCL6 test, accurate diagnosis, and early therapy initiation.

5.) How Likely Is It That Endometriosis Will Cause  IVF Failure?

Women suffering from recurrent IVF failure can use BCL6 test results to discover endometriosis as the reason for their struggles. Endometriosis is a condition that alters the reproductive organs or the hormonal environment. It causes inflammation and implants in the uterine lining. This makes it difficult for a viable embryo to implant in the uterus.

6.) In What Ways Does Silent Endometriosis Diagnosis Affect an Individual’s Fertility?

The main symptoms of silent endometriosis are recurrent pregnancy loss and failed implantations. IVF Patients experience zero occurrences of the typical symptoms of endometriosis.

It affects the uterine lining, ovaries, and fallopian tubes, impeding the fertility of an individual. Inflammation on the uterine lining makes it impossible for an embryo to implant and grow on the uterine wall. Implants on the fallopian tube impede the eggs from moving toward the sperm for fertilization.

Tackle Infertility by Starting Endometriosis Treatment Now

The BCL6 test is a safe procedure that may help identify BCL6 & endometriosis as the cause of infertility amongst most women suffering from IVF failure. Endometriosis symptoms in women can range in intensity from barely perceptible to crippling pain. If you experience any of these symptoms or have experienced unexplained infertility, seek medical treatment. Various treatments can help identify and treat endometriosis, increasing the chances of successful implantation and pregnancy.

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