Should I Take Meloxicam at Night or in The Morning?

Meloxicam is a nonsteroidal anti-inflammatory medication (NSAID) used largely to treat the arthritic pain. It is not available without a prescription and cannot be gotten without one. Meloxicam is a medication that is used to treat the pain, soreness, edema, and stiffness caused by osteoarthritis (arthritis caused by a breakdown of the joint lining) and rheumatoid arthritis (arthritis caused by swelling of the lining of the joints).

Meloxicam is also used in children 2 years of age and older to treat the pain, soreness, edema, and stiffness caused by juvenile rheumatoid arthritis (a kind of arthritis that affects children).

As someone suffering from Arthritis or another similar pain disease and having to take meloxicam frequently, the question remains: “Should I take Meloxicam at night or in the morning?” When will it be most effective at relieving pain?

What is Meloxicam?

Meloxicam is a prescription medication. It is available in three forms: oral tablet, injectable, and oral capsule. Meloxicam oral tablet is marketed under the brand name Mobic.

Meloxicam oral tablet is also a generic medication. Generic medications are typically less expensive than brand-name drugs. They may not be accessible in all strengths or forms as a brand-name medicine in some circumstances.

How Does Work Meloxicam?

Meloxicam belongs to the nonsteroidal anti-inflammatory medication class (NSAIDs). NSAIDs aid in the relief of pain, inflammation, and fever. It is unknown how this medicine reduces pain. It may help reduce swelling by reducing prostaglandin levels, a hormone-like molecule that normally induces inflammation.

How Should Meloxicam Be Used?

Meloxicam is available as a tablet and as an oral solution (liquid). It is administered once day, with or without food. Meloxicam should be taken every day at the same time. Follow the directions on your prescription label carefully, and if you have any questions, ask your doctor or pharmacist for clarification.

This medication should only be used at the lowest effective dose for the shortest possible time. Body weight, other medical concerns, and other prescriptions can all have an impact on the pharmaceutical dosage that a person requires. If your doctor has recommended a dose that differs from the ones shown here, do not change the dosage of your prescription without first visiting your doctor.

When using this drug, it is crucial to follow your doctor’s instructions. If you forget to take a dose, skip it and resume your regular dosing schedule. Do not take a double dose to make up for a missed dose. Consult your doctor or pharmacist if you are unsure what to do if you have missed a dose.

How Much Meloxicam Can I Take in One Day?

Meloxicam’s highest safe daily oral dose for adults, regardless of form, is 15 milligrams (mg). People with kidney disease may be unable to use this drug or may require a lower dose.

Meloxicam’s highest recommended oral dose for children weighing at least 60 kg (132 lbs) is 7.5 mg once day. Increasing the dose in children has no effect on the drug’s effectiveness. Meloxicam tablets should not be used by children under the age of 12 or who weigh less than 60 kg (132 lbs).

How Should Meloxicam Tablets Be Taken?

  • Read the manufacturer’s printed information leaflet from within the pack before you begin taking meloxicam. The booklet will provide you with additional information on the pills as well as a complete list of potential adverse effects.
  • Take meloxicam exactly as prescribed by your doctor. The typical dose is one pill per day. You will be given either 7.5 mg or 15 mg tablets to take.
  • With a sip of water, swallow the tablet whole.
  • Take each dose with a snack or shortly after eating a meal, and stay hydrated while taking meloxicam.
  • If your doctor has prescribed melt-in-the-mouth (orodispersible) tablets, follow these steps:
  • First, moisten your mouth with water if necessary.
  • Remove the tablet from its package, being careful not to get it.
  • Place the tablet on your tongue and let it dissolve gradually. This should take no more than five minutes.
  • Drink a large glass of water after five minutes and take the dissolved tablet.
  • Do not chew or swallow the tablet until it has dissolved.
  • Try to take your doses at the same time every day to assist you to remember to do so.
  • If you forget to take a dose, take it as soon as you recall, along with a snack. Skip the missing dose if you don’t recall until the next day. Do not combine two doses to make up for a missed dosage.

Should I Take Meloxicam at Night or in The Morning

A new study published in the journal Scientific Reports suggests that taking NSAIDs like meloxicam during the day may be better to taking them at night (such as before bed). Meloxicam can take up to two weeks to fully take action. Some changes in pain, edema, discomfort, or stiffness may be visible within 24 to 72 hours, but a significant difference in pain levels may take longer.

After taking this medication, do not lie down for at least 10 minutes. If you are taking this medication in liquid form, gently shake the bottle before each dose.

Dosages of Meloxicam

Meloxicam is usually taken once a day for osteoarthritis and rheumatoid arthritis. Meloxicam’s maximum daily dose for individuals with osteoarthritis or rheumatoid arthritis is 15 mg per day. The standard dose for children with juvenile rheumatoid arthritis is 0.125 mg/kg each day. Meloxicam’s maximum daily dose in children is 7.5 mg.

Meloxicam can take up to two weeks to fully take action. Pain, swelling, discomfort, or stiffness may improve in some persons within 24 to 72 hours. It may take a few months for some people to notice an improvement in their symptoms. The time it takes to feel better after taking meloxicam depends on the dosage.

According to clinical pharmacist Nonye Uddoh, “meloxicam reduces the pain, edema, and inflammation associated with arthritis.” When taken orally, it begins to operate within 30 minutes but reaches its greatest efficacy after 4 hours. It has a half-life of 15 to 20 hours, which means it takes 15 hours to remove half of it from your body.”

A missing dose should be administered as soon as possible after it is remembered. If your next dose is approaching, skip the missing dose and resume your regular dosing regimen. Meloxicam should not be taken in two doses.

Does Meloxicam Have a Boxed Warning?

Yes, meloxicam, like all NSAIDs, comes with a Boxed Warning outlining major safety concerns such as stomach and intestinal hemorrhage, as well as cardiac risks. These occurrences might happen at any time and without warning.

  • NSAIDs can raise the chance of a heart attack or stroke, both of which can be fatal.
  • NSAIDs increase the chance of significant digestive tract symptoms such as bleeding, ulcers, and tears in the stomach or intestines, which can be fatal.
  • Patients over the age of 65, as well as those with a history of peptic ulcer disease and/or digestive tract (gastrointestinal) bleeding, are at a higher risk of major GI events.
  • If you are having coronary artery bypass graft (CABG) surgery, you should not take meloxicam. Consult your doctor about this.

Is Mobic The Same As Meloxicam?

Meloxicam is marketed under the brand name Mobic. Previously, it was available as a 7.5 mg/5ml oral suspension. However, it was withdrawn off the market due to its limited efficacy and safety.

Mobic was specifically prescribed to treat arthritis, juvenile rheumatoid arthritis, osteoarthritis, and rheumatoid arthritis symptoms. Furthermore, it alleviates pain caused by inflammation, edema, stiffness, and joint pain. It used to work in 30 minutes but reached optimum efficacy after 4 hours of oral administration.

Despite its quick actions, Mobic had side effects like:

  • Discomfort in the stomach
  • gaining weight
  • Nausea
  • Vomiting
  • Gas
  • Dizziness
  • Nervousness
  • Bloating

What to Do If Meloxicam Doesn’t Work?

Celebrex is the best Meloxicam substitute. Celecoxib is marketed under the brand name Celebrex. Both function by blocking the production of prostaglandins.

Meloxicam substitutes that are routinely recommended include:

  • Ibuprofen
  • Celecoxib
  • Diclofenac
  • Voltaren
  • Naproxen
  • Diclofenac

The Advantages of Taking Meloxicam During the Day

Sometimes a doctor will recommend taking meloxicam once a day. You can take it either in the morning or at night. However, some people have claimed that taking meloxicam at night does not function as well as it does during the day.

In fact, according to a new study published in the journal Scientific Reports, taking nonsteroidal anti-inflammatory medicines (NSAID) during the day may be preferable because it reduces pain, inflammation, and swelling better.

Because of our biological clock and circadian rhythm, an NSAID like meloxicam may act better when taken during the day than than at night. This clock has an impact on pain, with sensitivity highest throughout the active part of the day.

As a result, maximal absorption and effectiveness are obtained when the medicine is delivered when we are awake and active. Other clinical investigations have indicated that timing the administration of an NSAID can maximize its effectiveness while minimizing its negative effects.

These medications have a strong anti-inflammatory impact when taken in the morning or early afternoon, but not in the evening. In the evening, you may have side effects such as indigestion, stomach ulcers, and acute kidney difficulties.

Meloxicam Side Effects

Meloxicam has both mild and severe side effects. The following are some of the most prevalent side effects of meloxicam usage. At least 1% of meloxicam users have had the negative effects listed below. Many of these negative effects are manageable, and some may fade away with time. Speak with your doctor if any of these side effects are severe or bothersome. This is not an exhaustive list of all possible side effects.

Some of the more common meloxicam side effects are as follows:

  • dizziness
  • headache
  • itching or a rash
  • stomach pain
  • Irritable bowel syndrome, indigestion, or heartburn are all symptoms of IBS.
  • Nausea
  • Constipation
  • Diarrhea
  • Gas
  • Indigestion
  • Ulcer in the mouth

The following are some examples of significant side effects and symptoms:

  • stomach and intestine issues
  • skin issues
  • kidney harm
  • Blood pressure has risen.
  • The heart attack
  • stroke
  • injury to the liver


Having worked with arthritis patients, I realize how terrible this condition can be. The pain of arthritis is often characterized and compared to labor agony, and it is severe enough for anyone to seek out the greatest pain-relieving drugs.

The best medicine at the best moment may have the best results. As a result, the question “Should I take Meloxicam at night or in the morning?” is immediately answered: Early in the morning on an empty stomach.

Frequently Asked Questions (FAQs) Should I Take Meloxicam at Night or in The Morning?

How long does meloxicam take to work for arthritis?

Your doctor will begin with a low dose and gradually raise it to allow your body to adjust to the NSAID. Because your body is designed to have a modest level of meloxicam, it takes around two weeks for this medication to start acting properly. You may notice tiny changes in your swelling, discomfort, and inflammation at first, but it normally takes a little longer to detect a larger decrease in these symptoms.

How Long Does Meloxicam Take To Work For Arthritis?

Meloxicam, in my experience, helps wonderfully for arthritis swelling and pain. The considerable relief experienced following an intake helps to alleviate discomfort and make a person feel good.

How long does meloxicam last?

Although both ibuprofen and meloxicam are nonsteroidal anti-inflammatory medicines (NSAIDs), meloxicam is a long-acting medication that can treat pain for up to 24 hours and is not used in conjunction with other medications.

Is weight gain a meloxicam adverse effect?

Meloxicam does not usually cause weight gain or loss. However, fluid retention is a common adverse effect, observed in 0.6% to 4.5% of those taking it. If fluid retention is not managed, it can cause cardiovascular issues and, eventually, congestive heart failure.

One effect of fluid retention is an unintentional increase in body weight. So, if you gain weight, it may affect fluid retention. Consult your doctor right away.

Is Meloxicam safe to take on a daily basis?

All drugs may cause certain negative effects. As a result, taking meloxicam for an extended period of time may raise the risk of stomach or intestinal bleeding, ulcers, or perforations. If you want to take Meloxicam on a daily basis for an extended period of time, you should visit your doctor. Meloxicam may cause sleeplessness; therefore, it is best to take it in the morning.

Is it safe to consume coffee when taking meloxicam?

Avoid drinking coffee while taking meloxicam since it may cause side effects. Caffeine in coffee, tea, energy drinks, and soft drinks can interact with medicine. Coffee also contains tannins, which are chemicals. Tannins can bind to many drugs, reducing the amount of medicine your body can absorb.

What are the most serious meloxicam side effects?

Heart attack, chest discomfort, stroke, stomach and intestinal difficulties, liver damage, elevated blood pressure, water retention, skin problems, or renal damage, such as dark urine, are all serious adverse effects.

It is critical to be aware of any indications that may indicate you are experiencing serious adverse effects from taking this medicine. Refer to your healthcare practitioner immediately away to get your condition handled.

What should you avoid when taking meloxicam?

Meloxicam may interact with other medications you are currently taking. Antidepressants or anxiety pills, corticosteroids, cancer meds, transplant drugs, bipolar disorder pills, blood pressure pills, and other medications can all interact with it.

Because it is an NSAID, it can interact with other NSAIDs such as aspirin, ibuprofen, and blood thinners. So, in order to get a better prescription, tell your doctor about your medical history and any medications you’re now on.

What Time of Day Is the Best to Take Meloxicam?

Is it better to take meloxicam (Mobic) in the morning or at night? It makes no difference when you take meloxicam (Mobic), as long as you do it at roughly the same time every day. In order to avoid stomach discomfort, take this drug with food or a small snack.

What anti-arthritic medication is more potent than meloxicam?

Mobic peak concentrations might be obtained up to 5 hours after administration. A second peak, however, comes 12 to 14 hours following the first dose. This means that while Celebrex acts faster than Mobic, the effects of Mobic may remain longer.

Meloxicam or ibuprofen: which is safer?

Meloxicam is a powerful pain reliever that should not be used without first contacting a doctor. However, investigations have shown that acute kidney injury is more common in patients treated with ibuprofen than in those treated with meloxicam.

Can Tramadol and Meloxicam be taken together?

Tramadol and Meloxicam are not dangerous when taken together. After repeated administration, no notable medication responses were seen. It sometimes improves the property as well.

Meloxicam is safe for children?

Meloxicam is not suitable for children. It can cause severe health problems, such as eye inflammation and skin peeling. You can also use paracetamol as an option.

Meloxicam can cause rashes?

Meloxicam overdosage can result in a variety of adverse effects. Skin rashes and peeling are two examples.

Is it safe to drink coffee while taking Meloxicam?

It is best not to drink coffee immediately after taking Meloxicam. It has the potential to interfere with your gut health and diminish Meloxicam’s operating ability.

Is meloxicam keeping you awake at night?

Meloxicam’s side effects do not include drowsiness (in fact, meloxicam can cause sleeplessness), but they do include dizziness. However, headache is a common and minor side effect of meloxicam.

Does meloxicam relieve pain right away?

According to clinical pharmacist Nonye Uddoh, “meloxicam reduces the pain, edema, and inflammation associated with arthritis.” When taken orally, it begins to operate within 30 minutes but reaches its greatest efficacy after 4 hours. It has a half-life of 15 to 20 hours, which means it takes 15 hours to remove half of it from your body.”

When should you avoid using meloxicam?

Unless your doctor instructs you otherwise, do not take meloxicam during or after 20 weeks of pregnancy. Call your doctor if you become pregnant while taking meloxicam. Tell your doctor or dentist that you are taking meloxicam if you are undergoing surgery, including dental surgery.

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